PREFORMULATION STUDIES OF STAVUDINE FOR TARGETED DRUG DELIVERY SYSTEM

Preformulation and Formulation Studies of Novel pH Independent Controlled Release Drug Delivery System of Quetiapine Fumarate

Advent of pharmacology, combinatorial chemistry and High Through Put Screening offered large number of synthetic drugs as a therapeutic substances. These molecules are potent to elucidate their pharmacological activity. However, pharmacokinetic properties of such molecules are rate limiting factors for its safety as well as efficacy. Most of the synthetic drug available so far in market are eit...

Advances in Targeted Drug Delivery

Advances in Targeted Drug Delivery

Liver Targeted Drug Delivery System

Targeted drug delivery or site-specific drug delivery system has the potential to increase local drug concentrations and thereby increase the effectiveness of the medicines with fewer side effects. Liver diseases especially liver cancer is one of the most prevalent cancers, with a high mortality. Due to high toxicity and poor specificity of the chemotherapeutic agents the present method of trea...

Phytosome: Drug Delivery System for Polyphenolic Phytoconstituents

      Several plant extracts and phytoconstituents, despite having excellent bioactivity in vitro, demonstrate less or no in vivo actions due to their poor lipid solubility or improper molecular size or destruction in gut. Drug delivery system for polyphenolic phytoconstituents (phytosomes) was prepared by complexing polyphenolic phytoconstituents with phospholipid mainly phosphatidylcholine wh...